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The Side Effects Of Steroids And More
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Everyone has hormones, and hormones are chemical messengers that tell your cells, organs and systems how to behave. steroids for sale uk Increasing or decreasing the amount of these agents can have a significant impact on how your body looks, feels and performs.
Testosterone is a naturally occurring hormone that has both anabolic and androgenic properties. Anabolism is what we bodybuilders look for in a steroid. Anabolism simply means it promotes muscle growth. Androgenic refers to an increase in your male sexual characteristics such as facial hair, deep voice and development of the genitals. Both men and women produce testosterone; men produce it in their testicles and women in their ovaries. Men, though, typically have 10 times more testosterone which is why we guys are generally stronger, leaner and more muscular than women.
Anabolic steroids, the subject of this report, are all synthetic forms of testosterone. These anabolic and androgenic effects of steroids are the reason why steroids are often known as AAS – which is short for anabolic, androgenic steroids.
Because of the desirable effects of testosterone, athletes and bodybuilders have often sought out ways to increase their testosterone levels. In the days of ancient Rome, gladiators often feasted on bulls’ testicles in an effort to capture some of the animal’s legendary size and strength! More recently, natural testosterone boosters containing herbs like horny goat weed, tribulus terrestris and bulbine natalensis have become very popular, but in truth, there is really only one that is worth using. It is so good in fact, that it can be used pre-cycle to prime your natural testosterone production, getting it as high as humanly possible and post cycle to restore your testosterone production that has been temporarily suppressed while you were on the juice.
AAS are available in two forms – in tablet or pill form (usually referred to as orals) and as an injectable. Oral AAS, such as Dianabol (methandrostenolone), Anadrol 50 (oxymetholone) and Halotestin (fluoxymesterone), can be toxic when taken in high doses or for prolonged periods of time. They can be toxic because they have to be chemically altered or methylated so that they will not be switched off by your liver and rendered virtually useless.
Unfortunately, the alteration that makes oral steroids bio-available, is also what increases toxicity and makes many oral steroids very liver-unfriendly. It is important to note, however, that it is not testosterone that is hard on the liver but the methylation necessary to produce an orally effective steroid that is the problem. That is why most in-the-know AAS users avoid oral-only steroid cycles or stack moderate amounts of orals with larger amounts of injectable steroids. Oral steroids have a very short lifespan of effectiveness which means they have to be taken frequently – every few hours in general. And although injecting may seem a little daunting, injectable steroids are generally safer and much more effective than oral steroids.
Testosterone is a naturally occurring hormone that has both anabolic and androgenic properties. Anabolism is what we bodybuilders look for in a steroid. Anabolism simply means it promotes muscle growth. Androgenic refers to an increase in your male sexual characteristics such as facial hair, deep voice and development of the genitals. Both men and women produce testosterone; men produce it in their testicles and women in their ovaries. Men, though, typically have 10 times more testosterone which is why we guys are generally stronger, leaner and more muscular than women.
Anabolic steroids, the subject of this report, are all synthetic forms of testosterone. These anabolic and androgenic effects of steroids are the reason why steroids are often known as AAS – which is short for anabolic, androgenic steroids.
Because of the desirable effects of testosterone, athletes and bodybuilders have often sought out ways to increase their testosterone levels. In the days of ancient Rome, gladiators often feasted on bulls’ testicles in an effort to capture some of the animal’s legendary size and strength! More recently, natural testosterone boosters containing herbs like horny goat weed, tribulus terrestris and bulbine natalensis have become very popular, but in truth, there is really only one that is worth using. It is so good in fact, that it can be used pre-cycle to prime your natural testosterone production, getting it as high as humanly possible and post cycle to restore your testosterone production that has been temporarily suppressed while you were on the juice.
AAS are available in two forms – in tablet or pill form (usually referred to as orals) and as an injectable. Oral AAS, such as Dianabol (methandrostenolone), Anadrol 50 (oxymetholone) and Halotestin (fluoxymesterone), can be toxic when taken in high doses or for prolonged periods of time. They can be toxic because they have to be chemically altered or methylated so that they will not be switched off by your liver and rendered virtually useless.
Unfortunately, the alteration that makes oral steroids bio-available, is also what increases toxicity and makes many oral steroids very liver-unfriendly. It is important to note, however, that it is not testosterone that is hard on the liver but the methylation necessary to produce an orally effective steroid that is the problem. That is why most in-the-know AAS users avoid oral-only steroid cycles or stack moderate amounts of orals with larger amounts of injectable steroids. Oral steroids have a very short lifespan of effectiveness which means they have to be taken frequently – every few hours in general. And although injecting may seem a little daunting, injectable steroids are generally safer and much more effective than oral steroids.
Hard Gainer? Discover How To Develop Slabs Of Rock Difficult Muscle Mass Now
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Of all the injectable steroids available, testosterone is arguably the best. Testosterone is very versatile, provides the best muscle and strength gains per milliliter of drug, and offers the best value for your money in terms of benefit per dollar spent. Plus, testosterone, unlike other more exotic drugs, is widely available.
Injectable testosterone is much less liver toxic. It is a suspension of the active form of the testosterone molecule mixed into sterile oil or, sometimes, into water. You administer injectable testosterone via deep, intramuscular injection. Usually, guys inject test into the glutes, deltoids or quads. For the most part, injectable testosterone is much longer lasting than oral steroids and has an active lifespan of between a few days to several weeks depending on the type used.
Injectable testosterone is available in several forms or esters. A particular testosterone’s ester refers to how its chemical structure has been changed to alter how long it remains active in your body after your injection. The time that a steroid remains active in your body is the steroid’s half-life.
throughout your steroid cycle using the least amount of testosterone possible.
If you find what I am going to share with you about the half-life of the top 5 testosterones valuable, then I hope you will check out my 5-week Ultimate Steroid Cycles Master Course, which I make available to the public four times a year. In the Ultimate Steroid Cycles Master Course, each week, for five weeks, I will share with you the secret information you need to learn about the half-life of ALL the other major anabolic steroids so that you are truly equipped to design the Ultimate Steroid Cycle. Once you understand the half-life for every steroid out there, we will look at the ultimate ways of combining them together in your cycle to help you build massive amounts of dry, lean muscle and melt off every last ounce of body-fat.
If you spend a few minutes surfing the internet looking for steroid information, you are bound to find articles that say that one type of testosterone is better than another. injectable steroids for sale It seems that everyone has a favorite type of testosterone, and while some people favor testosterone cypionate, others have a big love of enanthate. The difference between these and other types of testosterone is down to the addition of something called an ester and while esters are important, they are very misunderstood.
Purchasing Dianabol Oral Steroids
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Dianabol has little or no estrogenic, progestational or corticoid effects. We have noted changes in the transaminases (elevation), and in sulfobromophthalein retention with prolonged use.
Reports on the anabolic-androgenic ratio of ethylestrenol are inconsistent however, in doses providing anabolic response it showed little androgenic effect. In animal studies, ethylestrenol inhibits pituitary gonadotropin and has anti-estrogenic activity. Ethylestrenol appears to be moderately effective and quite free of side-effects. However, water and sodium retention have been evidenced with prolonged therapy.
dianabol for sale Morey, Stanley. Steroids (p. 16). Unknown. Kindle Edition.
So, what are anabolic steroids? Anabolic steroids, more properly referred to as anabolic–androgenic steroids (AAS), are simply synthetic replacements or derivatives of testosterone and nor-testosterone. This means that they are synthetic versions of the same hormones produced by your body. First synthesized by scientists in the 1930’s, this compound was first used to aid men who were unable to produce enough of their own testosterone to promote normal growth and sexual development.
Then, during World War II, it was found that this compound could be used to help soldiers suffering from malnutrition gain weight back and improve their performance on the battle field.
Later, after the war, athletes discovered this compound and began to use it to enhance their performance in competition. At the 1956 Olympics, this compound was credited for giving Soviet athletes the edge they needed to perform so well. After hearing that Soviet athletes were using this compound to dramatically improve their performance, an American physician named John Ziegler then developed a more selective form of the compound, an oral anabolic steroid called Dianabol, and distributed it to athletes. He quickly discovered that this greatly increased muscle mass and strength in the athletes who took the oral steroid.
After that, up until the early 1970s, the use of steroids exploded in popularity among Olympic athletes, as well as professional and college athletes. Finally, in 1975, the International Olympic Committee, (or IOC), finally took action against steroids, banning their use for all athletes performing in the Olympics.
Reports on the anabolic-androgenic ratio of ethylestrenol are inconsistent however, in doses providing anabolic response it showed little androgenic effect. In animal studies, ethylestrenol inhibits pituitary gonadotropin and has anti-estrogenic activity. Ethylestrenol appears to be moderately effective and quite free of side-effects. However, water and sodium retention have been evidenced with prolonged therapy.
dianabol for sale Morey, Stanley. Steroids (p. 16). Unknown. Kindle Edition.
So, what are anabolic steroids? Anabolic steroids, more properly referred to as anabolic–androgenic steroids (AAS), are simply synthetic replacements or derivatives of testosterone and nor-testosterone. This means that they are synthetic versions of the same hormones produced by your body. First synthesized by scientists in the 1930’s, this compound was first used to aid men who were unable to produce enough of their own testosterone to promote normal growth and sexual development.
Then, during World War II, it was found that this compound could be used to help soldiers suffering from malnutrition gain weight back and improve their performance on the battle field.
Later, after the war, athletes discovered this compound and began to use it to enhance their performance in competition. At the 1956 Olympics, this compound was credited for giving Soviet athletes the edge they needed to perform so well. After hearing that Soviet athletes were using this compound to dramatically improve their performance, an American physician named John Ziegler then developed a more selective form of the compound, an oral anabolic steroid called Dianabol, and distributed it to athletes. He quickly discovered that this greatly increased muscle mass and strength in the athletes who took the oral steroid.
After that, up until the early 1970s, the use of steroids exploded in popularity among Olympic athletes, as well as professional and college athletes. Finally, in 1975, the International Olympic Committee, (or IOC), finally took action against steroids, banning their use for all athletes performing in the Olympics.
What Can you do to gain size and strength when you buy Tri-Trenbolone
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Total exposure to ultraviolet rays of the sun influences hormone production. In fact, individuals in warmer climates reach puberty anywhere from two to four years earlier than individuals in areas that do not receive as much yearly exposure to the sun. Athletes should learn to take advantage of this natural ergogenic aid; in fact, the development of ultraviolet tanning booths could be of value.
Diurnal cycles are persisting daily rhythms of night and day variations. All animals have these cycles including humans. Tri-Trenbolone cycles are great for this.
The normal range in males for 17-ketosteroid excretion ranges from 6 mg./ 24 hour to 28 mg./ 24 hr. Obviously this is a rather broad range and in our experience we have learned to group people into three classes within this "normal" range (however, these are flexible because of the not uncommon exceptions to any rule). 1. Low Androgenic level (6-13 mg./ 24hrs.)
Individuals falling in this category usually have soft, "baby like" skin which is elastic and supple. Body hair is sparse, scalp hair full. Muscle tone is poor and muscle size is small. 2. Medium Androgenic level (14-20 mg./ 24 hrs.)
The majority of individuals are in this category. These individuals have characteristic male skin texture. Body hair and scalp hair are evident in ample amounts. Muscle tone and size are excellent. 3. High Androgenic levels (20-28 mg./ 24 hrs.)
This individual usually has rough skin texture (possibly having acne at some point in life), body hair is thick; however, baldness is common. This type of individual will usually be quite muscular and large in size.
First of all, we must state that steroid usage is unnecessary and undesirable in most cases. However, as has been discussed, athletes will use them, and as a physician and/ or trainer you should be able to intercede and use your knowledge to prevent their abuse.
Pre-pubescent individuals should be strongly advised against steroid use. It is at this stage that androgens can cause the most damage. Steroids are not the answer to success; it still boils down to good health, hard work and perseverance. The following steps should be followed prior to initiating steroid therapy using Tri-Trenbolone: Steroid Theory and Therapy
1. A complete blood work-up and urinalysis. Important parameters such as transaminase levels, cholesterol, and serum hormone levels in the blood workup should be followed closely. The excretion of 17-keto steroids in the urine should be noted to ascertain normal hormone level.
2. Once clinical studies are done, deficiencies or abnormalities can be noted and/ or corrected prior to steroid therapy (remember, steroids will alter many clinical levels). 3. A clinical analysis should be done midway into the steroid program to check for potential problem areas. 4. Steroid therapy should be carefully planned and only used prior to a competition. E. buy tri trenbolone Designing a Steroid Therapy Program.
Being A Star In Your Industry Is A Matter Of buying Turinabol
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The androgenic effect of virilization is probably the most common reported side-effect with steroid therapy. You can use Clenbuterol for weight loss.
The effects of virilization appear to be most evident in young males and women. In young males facial and body hair may become prominent as well as phallic enlargement and even precocious body development. Premature closure of the epiphyseal plates is also a problem that could become evident as a stunting of growth.
The effects in women are usually an increase in body and facial hair, deepening of the voice, increased sebaceous gland activity and changes in libido. Clitoral enlargement, male pattern baldness, and menstrual disturbances occur in some cases. The majority of these effects are totally reversible. Some authorities claim a few of the virilization effects in women are. irreversible (Wright, 1978).
In adult males the most common side-effects are increased body and facial hair, alopecia (hair loss), acne, deepening of the voice, prostatic hypertrophy. In some cases gynecomastia and even priapism may be noted.
These effects are reversible upon discontinuance of therapy. B. Alternations in the Physiology of Normal Reproductive Processes. The level of testosterone and the pituitary gonadotropins, FSH and ICSH control the production of testosterone and spermatozoa by the testes.
A reduction of testosterone in the blood stream promotes production of FSH and ICSH, which in turn stimulates testosterone production by the interstitial cells of the testes. clenbuterol buy When testosterone reaches normal levels, FSH and ICSH production is reduced.
Steroid administration can definitely alter the levels of the gonadotropins. A reduction in the levels of the gonadotropins over a prolonged period can lead to testicular atrophy and altered reproductive functioning.
Steroid administration can definitely alter the levels of the gonadotropins. A reduction in the levels of the gonadotropins over a prolonged period can lead to testicular atrophy and altered reproductive functioning.
Steroid hormones maintain high blood levels, thereby reducing the production of FSH and ICSH. The testes then stop functioning either partially or completely, causing atrophy due to lack of work. These effects are reversible. In fact, the new male contraceptives being developed are steroids. Clenbuterol is a great fat burner.
1. The liver plays a major role in carbohydrate metabolism and is the greatest store of glycogen in the body, approximately 20% of its total weight.
2. The liver also plays a large role in protein metabolism.
a. The liver removes amino groups from amino acids allowing the use of the remainder for energy. This process is termed deamination.
b. Transamination or transfer of amino groups from one amino acid to another is another important liver function. Two of the enzymes used in this last process are used as parameters to check for liver damage. These enzymes are Glutamic Oxaloacetic Transaminase (SGOT), which is found in liver, serum and heart, and Glutamic Pyruvic Transaminase (SGPT) which is found in serum, tissues and liver.
How Steroids Affect Your Sexuality.
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Oral activation of steroids has usually been accomplished by the introduction of a 17 a-alkyl substitute into the molecule. The presence of the alkyl group affects the metabolic course of the steroid by preventing its excretion as a 17 -ketosteroid. The presence of the alkyl group, however, is responsible for undesirable side-effects including hepatotoxicity. 17 a-alkyl substitutes have been reported to cause reversible, intrahepatic, obstructive jaundice due to cholestasis (Peters, 1958; Kaupp, 1962; Gilbert, 1963; Hogarth, 1963). Methenolone (dianabol), an orally active agent lacking the 17a-alkyl group, also caused changes in sulfobromophthalein retention and an increase in blood coagulation factors V and X (Kruskemper, 1966).
Oral steroids are generally not as active due to inactivation; therefore larger doses must be taken. steroid pills for sale Injectable steroids are as a rule low in hepatotoxicity and other side-effects associated with oral steroids. Dosage can also be maintained at lower levels. During "stacking," a method used to achieve a proper or desired ratio and effect, orals can effectively be utilized. Esterification of steroids
The formation of esters is an effective means of protection against metabolic inactivation and also produces a prolonged effect. The 17-B-hydroxy esters are an important group of steroids in this regard (acetates, propionates, n decanoates, plienylpropionates).
The esters of testosterone exhibit slightly higher values because of their resistance to metabolic inactivation and prolonged biological effect.
The esters, propionate, cypionate and enanthate are the most commonly used by athletes. The propionate form in aqueous solution is more androgenic than in the oil form, and is used by power lifters to attain a peak level in a short period of time. The cypionate and enanthate forms have duration of two to three weeks, the enanthate having a slightly longer duration than the cypionate.
The esters of testosterone produce excellent results, with low hepatotoxicity in subcutaneous form. Testosterone can be aromatized to estrogens and we have noted side-effects caused by this conversion, i.e., gynecomastia. Other common side-effects noted are:
1. acne 2. testicular degeneration 3. increased and/ or decreased libido These have all been seen to be temporary and reversible.
Dromostanolone is metabolized quickly and must be administered frequently. Dromostanolone is rather weak in biological activity.
Water retention and hypercalcemia are frequent problems with Dromostanolone. Conversion to estrogen in vivo is also a factor in the use of Dromostanolone. Oxymetholone is a potent, orally active anabolic agent with low androgenic activity. However, in doses required to achieve good anabolic effect considerable side-effects are noted (hypophysis inhibition; antiICSH effect).
Glucose tolerance is altered with prolonged use, producing hypoglycemic effect. Edgren (1963) has also reported that the androgenic response with anadrol is markedly higher than indicated by seminal vesicle studies. Oxymetholones popularity with powerlifters also indicates greater androgenic effect than research indicates. It also comes in high dosage per tablet (50 m.g./ tablet).
Does Creatine Function To Improve Muscle Mass Dimension And Strength?
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Although the injectable and oral steroids are the most well-known, there are also other mechanisms of delivery. German athletes were the first to use a steroid based nasal spray used much like a decongestant, and has been shown to leave the system after only three days. Skin patches and transdermals are also being utilized. The drug is found on the patch (or in the gel) and is absorbed into the body through the skin and into the bloodstream. Another method of steroid
delivery is by sublingual tablets. These tablets are placed under the tongue and dissolved. The reason for this is that the blood vessels in the mouth, specifically under the tongue, are very close to the surface, causing a rapid infusion of the compound into the bloodstream. During a heart attack, individuals immediately put nitroglycerine tablets under the tongue to stop the myocardial infarction from progressing. Infusion of the compound into the bloodstream takes only a few seconds. The down side of sublingual administration routes is the relatively low amounts of active drug that can be supplied.
steroids for sale uk All oral steroids must undergo oral activation before the drug can be fully absorbed and release its effects on bodily tissues. Although the proposed mechanisms of oral activation are effective in activating the steroid in vivo, the damage to the surrounding bodily tissue is of great concern. Moreover, these same oral activation techniques have been used in many popular prohormones as well, making the athlete taking them susceptible to permanent internal damage.
All oral steroids must undergo oral activation before the drug can be fully absorbed and release its effects on bodily tissues. Although the proposed mechanisms of oral activation are effective in activating the steroid in vivo, the damage to the surrounding bodily tissue is of great concern. Moreover, these same oral activation techniques have been used in many popular prohormones as well, making the athlete taking them susceptible to permanent internal damage.
Testosterone is the most fundamental androgen in existence, and is the compound to which all other steroids are compared. However, the activity of testosterone is considerably ineffective in oral administration, making injection the optimal alternative. It has been the goal of steroid researchers to create an orally active form of testosterone to eliminate the need to inject the drug directly into the body. Orally taken drugs are easier for the user and eliminate the risk of infection due to injection. In order to increase the bioavailability of oral testosterone, a synthetic alteration was used known as 17-alpha alkylation, which is discussed thoroughly in the steroid profiles chapter of this book. This process involves the addition of one alkyl group (ethyl or methyl) to the alpha position of the 17th carbon on the steroid molecule. Doing so purportedly prevents the primary pathway of androgen deactivation from being utilized. This will prevent the oxidation of the 17-keto steroid, which will allow the drug to survive what is known as the "first pass" through the liver. When a drug that is not 17 alpha alkylated, the liver will cause the metabolic degradation of the steroid, rendering it useless.
delivery is by sublingual tablets. These tablets are placed under the tongue and dissolved. The reason for this is that the blood vessels in the mouth, specifically under the tongue, are very close to the surface, causing a rapid infusion of the compound into the bloodstream. During a heart attack, individuals immediately put nitroglycerine tablets under the tongue to stop the myocardial infarction from progressing. Infusion of the compound into the bloodstream takes only a few seconds. The down side of sublingual administration routes is the relatively low amounts of active drug that can be supplied.
steroids for sale uk All oral steroids must undergo oral activation before the drug can be fully absorbed and release its effects on bodily tissues. Although the proposed mechanisms of oral activation are effective in activating the steroid in vivo, the damage to the surrounding bodily tissue is of great concern. Moreover, these same oral activation techniques have been used in many popular prohormones as well, making the athlete taking them susceptible to permanent internal damage.
All oral steroids must undergo oral activation before the drug can be fully absorbed and release its effects on bodily tissues. Although the proposed mechanisms of oral activation are effective in activating the steroid in vivo, the damage to the surrounding bodily tissue is of great concern. Moreover, these same oral activation techniques have been used in many popular prohormones as well, making the athlete taking them susceptible to permanent internal damage.
Testosterone is the most fundamental androgen in existence, and is the compound to which all other steroids are compared. However, the activity of testosterone is considerably ineffective in oral administration, making injection the optimal alternative. It has been the goal of steroid researchers to create an orally active form of testosterone to eliminate the need to inject the drug directly into the body. Orally taken drugs are easier for the user and eliminate the risk of infection due to injection. In order to increase the bioavailability of oral testosterone, a synthetic alteration was used known as 17-alpha alkylation, which is discussed thoroughly in the steroid profiles chapter of this book. This process involves the addition of one alkyl group (ethyl or methyl) to the alpha position of the 17th carbon on the steroid molecule. Doing so purportedly prevents the primary pathway of androgen deactivation from being utilized. This will prevent the oxidation of the 17-keto steroid, which will allow the drug to survive what is known as the "first pass" through the liver. When a drug that is not 17 alpha alkylated, the liver will cause the metabolic degradation of the steroid, rendering it useless.
Some researchers suggest that these changes in glucose metabolism may predispose an individual to atherosclerosis due to increased triglyceride levels. Increases in triglyceride levels may in turn alter cholesterol metabolism, raising cholesterol levels.
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Some researchers suggest that these changes in glucose metabolism may predispose an individual to atherosclerosis due to increased triglyceride levels. Increases in triglyceride levels may in turn alter cholesterol metabolism, raising cholesterol levels. However, evidence to support this is inconclusive. Cortisol (body's major stress hormone) is also affected by Deca Durabolin steroids, especially oral therapy. They appear to interfere with cortisols breakdown in the liver, leading to increased levels in the serum. This may also predispose one to atherosclerosis, because cortisol has a marked effect on protein, carbohydrate and lipid metabolism.
However, elevated levels of cortisol appear to allow individuals to train harder and longer. Steroids also produce changes in the blood clotting factors (II, V, VII, X), but this remains rather vague in meaning.
In some cases elevation in blood pressure and increased nervous tension are noted. Again, these effects are noted most frequently with oral steroids. These changes may be in part due to fluid and/ or electrolyte level changes.
A number of other side-effects are noted in some patients. A common on ~ is muscle cramps, which have hobbled many athletes. Aggression is a side-effect which many athletes treat as a positive side-effect. Gastrointestinal disorders, headaches, dizziness, and light-headedness are occasional side-effects. Skin rashes, pain at injection site have also been reported. Steroids, evidenced in a depressed PBI, alter thyroid function tests.
Steroid therapy does produce side-effects; however, many of these can be alleviated or avoided if precautions are taken. Vitamin and mineral supplementation should be standard, especially vitamins C, B vitamins and the minerals calcium and iron. These vitamins and minerals are depleted during steroid therapy.
The proper selection of steroids and their usage is strongly advised. From previous sections, we can ascertain that the safest steroids are the injectable forms in most cases such as Deca Durabolin. The increased efficiency and their reduced side-effects make them more desirable than oral products.
However, for desirable effects "stacking" with an injectable-oral combination is sometimes necessary.
In conclusion, we must say that there are many known and unknown risks in steroid use. Dr. F. L. Johnson, of the University of Washington School of Medicine, feels that side-effects may be slight or altogether absent in normal individuals during short-term use. However, long-term effects are still unknown.
Hormone level varies with age as can be noted in The use of 17-ketosteroid excretion is an excellent indication of endogenous hormone production. http://www.steroids-on-line.eu/Buy-Deca-Durabolin.html Peak hormone levels are achieved at approximately 20 to 21 years of age. An approximate 10% drop in hormone level is seen around 30 years of age (corresponding with a 10% drop in B.M.R.) as seen in figure 9B. Another drop of approximately 10% is noted at around 40 and again at 50. Hormone levels in healthy individuals appear to remain stable after 50. Nutrition and hormone levels become critical training factors after 40 years of age (Bass, 1980). A 20% drop in hormone level with a corresponding drop in B.M.R. is noted between the ages of 20 to 40.
Top 4 Effective Clenbuterol Tips That Work For Any Type Of Athelete
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Cholestasis, which is a lessened or impaired bile flow, can occur on steroid therapy. This causes an accumulation of bilirubin, which is excreted in the urine. Whenever total impairment of bile flow occurs, jaundice can occur, which can be fatal. Whilst Turinabol is very mild and can be taken with the least damage to the liver.
The liver is also important in the detoxification, inactivation and removal of many substances such as urea, toxins and hormones and other toxic products. This ability of the liver to eliminate strange or foreign substances is the basis for several liver function tests.
One of these liver function tests is the Bromosulfophthalein (BSP) retention/ excretion test, BSP being a white dye, which competes directly with bile for excretion. Several enzymes are also used for liver function tests such as SGOT, SGPT, lactic dehydrogenase and alkaline phosphatase. Elevation in BSP retention and in SGOT and SGPT usually occur early in steroid therapy, and primarily with orals. buy turinabol These elevations appear to be dose dependent in some cases (Wright, 1979). Elevations of bilirubin and alkaline phosphatase are seen later in steroid therapy and appear to represent greater liver damage. Prolonged treatment of hospitalized patients with high dosages of steroids has produced cholestasis and jaundice, and in some cases fatalities.
However, the studies that have been reported on normal athletes are inconclusive and tend to indicate both mild and infrequent changes in liver health, and that normal chemistry levels were achieved within two weeks.
Most of the chemical changes were noted on oral steroids and these were reported to be reversible. Transaminase (SGOT, SGPT) levels appear to be the most commonly observed .chemical changes during steroid therapy. However, the levels of increase usually are only two to three times normal on heavy dosages, where in severe liver disease these levels are ten times normal, or higher.
Changes in transaminase levels are common after therapy with many common drugs (oral· contraceptives, alcohol, antibiotics) and even severe excercise.
Several eminent researchers feel that these transient transaminase changes have not been demonstrated to be associated with pathology of the liver and may in fact actually reflect increased protein synthesis in the liver.
In reveiw, it appears that oral steroids, because of their chemical alteration to reduce deactivation by the liver, normally cause more changes than injectables. Also, these changes appear to be rather transient, often reaching a peak about three weeks after initiation of therapy (approximately three weeks).
Steroid therapy appears to alter glucose metabolism. It has been reported that individuals on oral steroids show a reduced resting blood glucose level and a reduction in oral and intravenous glucose tolerance. A marked resistance to insulin was also noted. Therapy with oral Turinabol steroids led to increases in insulin secretion.
The liver is also important in the detoxification, inactivation and removal of many substances such as urea, toxins and hormones and other toxic products. This ability of the liver to eliminate strange or foreign substances is the basis for several liver function tests.
One of these liver function tests is the Bromosulfophthalein (BSP) retention/ excretion test, BSP being a white dye, which competes directly with bile for excretion. Several enzymes are also used for liver function tests such as SGOT, SGPT, lactic dehydrogenase and alkaline phosphatase. Elevation in BSP retention and in SGOT and SGPT usually occur early in steroid therapy, and primarily with orals. buy turinabol These elevations appear to be dose dependent in some cases (Wright, 1979). Elevations of bilirubin and alkaline phosphatase are seen later in steroid therapy and appear to represent greater liver damage. Prolonged treatment of hospitalized patients with high dosages of steroids has produced cholestasis and jaundice, and in some cases fatalities.
However, the studies that have been reported on normal athletes are inconclusive and tend to indicate both mild and infrequent changes in liver health, and that normal chemistry levels were achieved within two weeks.
Most of the chemical changes were noted on oral steroids and these were reported to be reversible. Transaminase (SGOT, SGPT) levels appear to be the most commonly observed .chemical changes during steroid therapy. However, the levels of increase usually are only two to three times normal on heavy dosages, where in severe liver disease these levels are ten times normal, or higher.
Changes in transaminase levels are common after therapy with many common drugs (oral· contraceptives, alcohol, antibiotics) and even severe excercise.
Several eminent researchers feel that these transient transaminase changes have not been demonstrated to be associated with pathology of the liver and may in fact actually reflect increased protein synthesis in the liver.
In reveiw, it appears that oral steroids, because of their chemical alteration to reduce deactivation by the liver, normally cause more changes than injectables. Also, these changes appear to be rather transient, often reaching a peak about three weeks after initiation of therapy (approximately three weeks).
Steroid therapy appears to alter glucose metabolism. It has been reported that individuals on oral steroids show a reduced resting blood glucose level and a reduction in oral and intravenous glucose tolerance. A marked resistance to insulin was also noted. Therapy with oral Turinabol steroids led to increases in insulin secretion.
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Although the injectable and oral steroids are the most well-known, there are also other mechanisms of delivery. German athletes were the first to use a steroid based nasal spray used much like a decongestant, and has been shown to leave the system after only three days. Skin patches and transdermals are also being utilized. The drug is found on the patch (or in the gel) and is absorbed into the body through the skin and into the bloodstream. Another method of steroid
delivery is by sublingual tablets. These tablets are placed under the tongue and dissolved. The reason for this is that the blood vessels in the mouth, specifically under the tongue, are very close to the surface, causing a rapid infusion of the compound into the bloodstream. During a heart attack, individuals immediately put nitroglycerine tablets under the tongue to stop the myocardial infarction from progressing. Infusion of the compound into the bloodstream takes only a few seconds. The down side of sublingual administration routes is the relatively low amounts of active drug that can be supplied.
All oral steroids must undergo oral activation before the drug can be fully absorbed and release its effects on bodily tissues. Although the proposed mechanisms of oral activation are effective in activating the steroid in vivo, the damage to the surrounding bodily tissue is of great concern. Moreover, these same oral activation techniques have been used in many popular prohormones as well, making the athlete taking them susceptible to permanent internal damage.
All oral steroids must undergo oral activation before the drug can be fully absorbed and release its effects on bodily tissues. Although the proposed mechanisms of oral activation are effective in activating the steroid in vivo, the damage to the surrounding bodily tissue is of great concern. Moreover, these same oral activation techniques have been used in many popular prohormones as well, making the athlete taking them susceptible to permanent internal damage.
Testosterone is the most fundamental androgen in existence, and is the compound to which all other steroids are compared. However, the activity of testosterone is considerably ineffective in oral administration, making injection the optimal alternative. It has been the goal of steroid researchers to create an orally active form of testosterone to eliminate the need to inject the drug directly into the body. steroids for sale uk Orally taken drugs are easier for the user and eliminate the risk of infection due to injection. In order to increase the bioavailability of oral testosterone, a synthetic alteration was used known as 17-alpha alkylation, which is discussed thoroughly in the steroid profiles chapter of this book. This process involves the addition of one alkyl group (ethyl or methyl) to the alpha position of the 17th carbon on the steroid molecule. Doing so purportedly prevents the primary pathway of androgen deactivation from being utilized. This will prevent the oxidation of the 17-keto steroid, which will allow the drug to survive what is known as the "first pass" through the liver. When a drug that is not 17 alpha alkylated, the liver will cause the metabolic degradation of the steroid, rendering it useless.
delivery is by sublingual tablets. These tablets are placed under the tongue and dissolved. The reason for this is that the blood vessels in the mouth, specifically under the tongue, are very close to the surface, causing a rapid infusion of the compound into the bloodstream. During a heart attack, individuals immediately put nitroglycerine tablets under the tongue to stop the myocardial infarction from progressing. Infusion of the compound into the bloodstream takes only a few seconds. The down side of sublingual administration routes is the relatively low amounts of active drug that can be supplied.
All oral steroids must undergo oral activation before the drug can be fully absorbed and release its effects on bodily tissues. Although the proposed mechanisms of oral activation are effective in activating the steroid in vivo, the damage to the surrounding bodily tissue is of great concern. Moreover, these same oral activation techniques have been used in many popular prohormones as well, making the athlete taking them susceptible to permanent internal damage.
All oral steroids must undergo oral activation before the drug can be fully absorbed and release its effects on bodily tissues. Although the proposed mechanisms of oral activation are effective in activating the steroid in vivo, the damage to the surrounding bodily tissue is of great concern. Moreover, these same oral activation techniques have been used in many popular prohormones as well, making the athlete taking them susceptible to permanent internal damage.
Testosterone is the most fundamental androgen in existence, and is the compound to which all other steroids are compared. However, the activity of testosterone is considerably ineffective in oral administration, making injection the optimal alternative. It has been the goal of steroid researchers to create an orally active form of testosterone to eliminate the need to inject the drug directly into the body. steroids for sale uk Orally taken drugs are easier for the user and eliminate the risk of infection due to injection. In order to increase the bioavailability of oral testosterone, a synthetic alteration was used known as 17-alpha alkylation, which is discussed thoroughly in the steroid profiles chapter of this book. This process involves the addition of one alkyl group (ethyl or methyl) to the alpha position of the 17th carbon on the steroid molecule. Doing so purportedly prevents the primary pathway of androgen deactivation from being utilized. This will prevent the oxidation of the 17-keto steroid, which will allow the drug to survive what is known as the "first pass" through the liver. When a drug that is not 17 alpha alkylated, the liver will cause the metabolic degradation of the steroid, rendering it useless.
